Foreign Body Airway Obstruction

 

Introduction and Outcome Analysis

     To develop the best treatment for choking, Patrick took the approach that it was necessary

to consider possible treatments as sequences of specific treatments where a specific treatment

includes backslaps, delivering energy to a foreign body through creation of potential energy

(what became known as the Heimlich maneuver), finger sweeps, or placing the victim upside down

(children). It would be possible to evaluate a specific treatment such as what was to become the

Heimlich maneuver or a backslap using an energy model. But to evaluate treatment sequences

of any specific treatment would require "outcome analysis." Patrick began to develop what later

would become known as "outcome analysis" about 1960. The publication of Fundamentals of

Pattern Recognition in 1972 by Prentice Hall solidified the approach.

 

     In the early 1970's the medical community, for the most part, was not prepared to accept that

treatments could be evaluated using Statistical Pattern Recognition. Instead, the medical community

insisted that Double Blind Studies were needed, but this was not practical in the case of choking.

Patrick indicated that any outcome O could be evaluated for any treatment sequence Tby

computing an estimate of the conditional probability of the outcome O given the treatment sequence.

Thus, one needed to estimate:

 

                                p(O|Ti), for an outcome O for each treatment sequence T1, T2,.... TN.

 

More precisely, one would need a set of "training samples" x to learn or estimate this outcome

probability, so that the above expression should be replaced by:

 

                                p(O|Ti, x), for an outcome O for each treatment sequence T1, T2,.... TN,

                                given training samples for each treatment sequence.

 

     Using verified training samples from cases sent into talk shows, Patrick was able to estimate needed

probabilities. Dr Richard L. Day reviewed Patrick's outcome analysis and wrote that it was a "well designed

protocol" and "the arithmetic is not faulty." At the same time Dr. Day criticized the American Heart Association

data, writing "If Redding was correct when he belittled his data (Redding's American Heart Association data),

those data should not have been published." This illustrates how the journals controlled by AHA researchers could

publish flawed "peer reviewed" papers while a scientific paper on outcome analysis by Patrick was difficult to

publish.

 

     Dr. Edward Patrick wrote the surgeon general Dr. C. Everett Koop providing Dr. Koop with the literature and research

studies so the United States Department of Health & Human Services could independently review the information.

After reviewing the information, Dr Koop called and wrote Dr Patrick to tell him that he agreed with Patrick and

would so inform the American people.

 

Patrick Energy Model

 

     To model electomechanical energy conversion, the lungs/chest/diaphragm/muscles/ trachea can

be described as a system where the gas in the lungs has a volume and pressure and is connected

to an airway. In 1972 we considered a primitive model provided by Brown, Jacob and Stark where

the lung, for the purpose of gas flow, was represented as a cylinder with a plunger (or piston) where

the cylinder opened into a smaller cylinder (or tube - the airway). This motivated our construction of

the Patrick Energy Model for Foreign Body Airway Obstruction.

 

     Energy is stored in the lungs as potential energy related to the integral of pressure as it changes

with respect to a change in volume. Through conservation of energy and electomechanical energy

conversion, this potential energy can be converted into kinetic energy of a flying object.

Electromechanical energy conversion was established as a strong discipline in Electrical Engineering

education at the Massachusetts Institute of Technology (MIT) in the 1950 - 1970 time period. For

example, it has been used by Dr. Bose of MIT who's electromehanical energy conversion work is

all around us today - Bose speakers and Bose radios.

 

     In the case of music and speakers, the electromechanical energy conversion is from electrical

energy to acoustic energy. But in the case of foreign body airway obstruction, the Patrick Energy

Model deals with the conversion of Potential Energy, which is stored energy in a compressed gas,

to Kinetic Energy acquired by the obstructing object as it is removed.

 

     Let P be the pressure of gas in the lungs, V  the volume of this gas, dV the change in volume

as our maneuver is applied, M the mass of the obstructing object, and S the speed (velocity) obtained

by the object. Assuming no loss of energy to tissues or friction, the expression for the Patrick Energy

Model is:

 

                               Potential Energy    =    Kinetic Energy

 

                                       ∫PdV              =     (1/2)•M•S2

 

The speed at which the foreign body is expelled, given this ideal model, is:

 

                                        S  =  [2• PdV / M ]1/2

 

Thus the speed S at which the obstructing object flys out is higher as the mass of the object is smaller.

 

 

Pressure Alone Does Not Remove a Foreign Body Obstructing the Airway

 

     The best method to treat foreign body airway obstruction should deliver maximum kinetic energy

to the obstructing foreign body with velocity directed out of the airway. A major cause of confusion

has been the interpretation of pressure time curves with the erroneous belief that pressure alone

removes a foreign body. Experiments have been done on humans to measure the pressure at the

airway outlet (transducer in a face mask or at the end of an endotracheal tube if the individual is

intubated) vs time. Gordon compared the pressure of airway gas produced in response to backslaps

with that produced by the Heimlich maneuver, while Heimlich had plotted the pressure vs time for

the Heimlich maneuver. Gordon presented his findings in 1975 at the National Research Council of

the National Academy of Sciences joint meeting with the National Red Cross, and subsequently he

and his colleagues distributed them elsewhere. They argued that the pressure curves curves show a

higher peak pressure for backslaps than for the Heimlich maneuver and mistakenly concluded that

backslaps therefore are superior to the Heimlich maneuver in expelling foreign bodies.

 

     Also at the National Research Council conference in 1975, Patrick presented a paper showing

the fallacy of Gordon's conclusion that pressure alone removes a foreign body. Citing a model of the

lungs and airway utilizing electomechanical energy conversion which Patrick had developed in 1972,

Patrick explained that energy is required to remove a foreign body. If the treatment is a backslap

or the Heimlich maneuver, then energy results from pressure acting over time. He showed that energy

directed to move a foreign body is proportional to the area within the pressure-time curve (for the

segment of time concerned).

pressure acting over time